http://www.merlot.org:80/merlot/ A search of MERLOT materials Copyright 1997-2013 MERLOT. All rights reserved. Tue, 21 May 2013 08:33:51 PDT Tue, 21 May 2013 08:33:51 PDT http://www.merlot.org:80/merlot/images/merlot.gif http://www.merlot.org:80/merlot/ 44 34 http://www.merlot.org/merlot/viewMaterial.htm?id=442590 According to Textbook Revolution, a student-run site “dedicated to increasing the use of free educational materials by teachers and professors,” "This is the classic text on evolution. It is remarkable for its accessibility. Most seminal publications in science are intelligible only to expert readers. Darwin, in contrast, built his argument on simple logic and readily observed facts of nature – no special training is required to understand his work. It is a little wordy by modern standards, but definitely worth a look. All of Darwin’s work is in the public domain, and much of it is provided free for download in .txt format by the good people over at Project Gutenberg. The posted link will take you to a list of available publications by Charles Darwin, including two editions of the Origin of Species.״ http://www.merlot.org/merlot/viewMaterial.htm?id=442537 According to the author, "The book is intended as a help for students and researchers in the biomedical fields, enabling them to choose the best model for their dose-response data obtained from wet-lab experiments. The focus is on how to interpret and handle dose-response data, with a recommendation to down-play analytical methods developed before the era of personal computers, such as the Lineweaver–Burk and Scatchard data conversion, the null-methods by Gaddum and Schild, or the use of meaningless mathematical manipulations, as for instance the implementation of a Hill-exponentiation. Instead, when fishing for system constants, the readers learn how to get access to the free-way of analytical tools that offer forward formulated physical functions to be fixed with non-linear fitting procedures. The approach I have taken is different from that of many other textbooks on the analysis of equilibrium dose-responses, which follow in the tradition of data-linearization developed more than 70 years ago. A book in point is Segel's ‘Enzyme kinetics’ (1975), reissued as a non-revised edition in 1993 and still considered a standard textbook on enzyme kinetics: it lacks almost completely in analysis of the so-called two-state models.״ http://www.merlot.org/merlot/viewMaterial.htm?id=483017 This is a free, online textbook that "contains 2- and 3-dimensional, anatomical reference slides of zebrafish to support research and education worldwide. Hematoxylin & eosin histological slides, at various points in the lifespan of the zebrafish, have been scanned at 40x resolution and are available through a virtual slide viewer. 3D models of the organs are reconstructed from plastic tissue sections of embryo and larvae. The size of the zebrafish, which allows sections to fall conveniently within the dimensions of the common 1" x 3" glass slide, makes it possible for this anatomical atlas to become as high resolution as for any vertebrate. That resolution, together with the integration of histology and organ anatomy, will create unique opportunities for comparisons with both smaller and larger model systems that each have their own strengths in research and educational value. The atlas team is working to allow the site to function as a scaffold for collaborative research and educational activity across disciplines and model organisms.״