http://www.merlot.org:80/merlot/ A search of MERLOT materials Copyright 1997-2013 MERLOT. All rights reserved. Fri, 24 May 2013 18:48:39 PDT Fri, 24 May 2013 18:48:39 PDT http://www.merlot.org:80/merlot/images/merlot.gif http://www.merlot.org:80/merlot/ 44 34 http://www.merlot.org/merlot/viewMaterial.htm?id=591437 This course covers introductory microbiology from a systems perspective, considering microbial diversity, population dynamics, and genomics. Emphasis is placed on the delicate balance between microbes and humans, and the changes that result in the emergence of infectious diseases and antimicrobial resistance. The case study approach covers such topics as vaccines, toxins, biodefense, and infections including Legionnaire’s disease, tuberculosis, Helicobacter pylori, and plague. http://www.merlot.org/merlot/viewMaterial.htm?id=79167 Free 50-page workbook with structured self-paced learning exercises on anesthesia machines for use with the Virtual Anesthesia Machine (VAM) simulation at http://www.anest.ufl.edu/vam http://www.merlot.org/merlot/viewMaterial.htm?id=344988 "The course covers basic concepts of biomedical engineering and their connection with the spectrum of human activity. It serves as an introduction to the fundamental science and engineering on which biomedical engineering is based. Case studies of drugs and medical products illustrate the product development-product testing cycle, patent protection, and FDA approval. It is designed for science and non-science majors." http://www.merlot.org/merlot/viewMaterial.htm?id=591551 This course develops and applies scaling laws and the methods of continuum mechanics to biomechanical phenomena over a range of length scales. Topics include structure of tissues and the molecular basis for macroscopic properties; chemical and electrical effects on mechanical behavior; cell mechanics, motility and adhesion; biomembranes; biomolecular mechanics and molecular motors. The class also examines experimental methods for probing structures at the tissue, cellular, and molecular levels. http://www.merlot.org/merlot/viewMaterial.htm?id=591435 This course provides intensive coverage of the theory and practice of electromechanical instrument design with application to biomedical devices. Students will work with MGH doctors to develop new medical products from concept to prototype development and testing. Lectures will present techniques for designing electronic circuits as part of complete sensor systems. Topics covered include: basic electronics circuits, principles of accuracy, op amp circuits, analog signal conditioning, power supplies, microprocessors, wireless communications, sensors, and sensor interface circuits. Labs will cover practical printed circuit board (PCB) design including component selection, PCB layout, assembly, and planning and budgeting for large projects. Problem sets and labs in the first six weeks are in support of the project. Major team-based design, build, and test project in the last six weeks. Student teams will be composed of both electrical engineering and mechanical engineering students. http://www.merlot.org/merlot/viewMaterial.htm?id=591253 This class is a project-based introduction to the engineering of synthetic biological systems. Throughout the term, students develop projects that are responsive to real-world problems of their choosing, and whose solutions depend on biological technologies. Lectures, discussions, and studio exercises will introduce (1) components and control of prokaryotic and eukaryotic behavior, (2) DNA synthesis, standards, and abstraction in biological engineering, and (3) issues of human practice, including biological safety; security; ownership, sharing, and innovation; and ethics. Enrollment preference is given to freshmen. This subject was originally developed and first taught in Spring 2008 by Drew Endy and Natalie Kuldell. Many of Drew's materials are used in this Spring 2009 version, and are included with his permission. This OCW Web site is based on the OpenWetWare class Wiki, found at OpenWetWare: 20.020 (S09) http://www.merlot.org/merlot/viewMaterial.htm?id=591411 In this course problems from biological engineering are used to develop structured computer programming skills and explore the theory and practice of complex systems design and construction. The official course Web site can be viewed at: BE.180 Biological Engineering Programming. http://www.merlot.org/merlot/viewMaterial.htm?id=591621 This course introduces the basic driving forces for electric current, fluid flow, and mass transport, plus their application to a variety of biological systems. Basic mathematical and engineering tools will be introduced, in the context of biology and physiology. Various electrokinetic phenomena are also considered as an example of coupled nature of chemical-electro-mechanical driving forces. Applications include transport in biological tissues and across membranes, manipulation of cells and biomolecules, and microfluidics. http://www.merlot.org/merlot/viewMaterial.htm?id=591303 This seminar-format course provides an in-depth presentation and discussion of how engineering and biological approaches can be combined to solve problems in science and technology, emphasizing integration of biological information and methodologies with engineering analysis, synthesis, and design. Emphasis is placed on molecular mechanisms underlying cellular processes, including signal transduction, gene expression networks, and functional responses. http://www.merlot.org/merlot/viewMaterial.htm?id=591646 This subject deals primarily with kinetic and equilibrium mathematical models of biomolecular interactions, as well as the application of these quantitative analyses to biological problems across a wide range of levels of organization, from individual molecular interactions to populations of cells.