http://www.merlot.org:80/merlot/ A search of MERLOT materials Copyright 1997-2013 MERLOT. All rights reserved. Sun, 26 May 2013 01:16:36 PDT Sun, 26 May 2013 01:16:36 PDT http://www.merlot.org:80/merlot/images/merlot.gif http://www.merlot.org:80/merlot/ 44 34 http://www.merlot.org/merlot/viewMaterial.htm?id=343162 Medicines By Design aims to explain how scientists unravel the many different ways medicines work in the body and how this information guides the hunt for drugs of the future. Pharmacology is a broad discipline encompassing every aspect of the study of drugs, including their discovery and development and the testing of their action in the body. http://www.merlot.org/merlot/viewMaterial.htm?id=384633 This is one of the Merck Manuals that deals with Pharmacology topics such as Adverse Drug Reactions, Concepts in Pharmacotherapy, Drug Therapy in the Elderly, and others. Each sub-section has an Introduction along with Description of the Problem and Symptomology. http://www.merlot.org/merlot/viewMaterial.htm?id=349748 Hyperlinked Ganfyd pages by medical subject area http://www.merlot.org/merlot/viewMaterial.htm?id=442537 According to the author, "The book is intended as a help for students and researchers in the biomedical fields, enabling them to choose the best model for their dose-response data obtained from wet-lab experiments. The focus is on how to interpret and handle dose-response data, with a recommendation to down-play analytical methods developed before the era of personal computers, such as the Lineweaver–Burk and Scatchard data conversion, the null-methods by Gaddum and Schild, or the use of meaningless mathematical manipulations, as for instance the implementation of a Hill-exponentiation. Instead, when fishing for system constants, the readers learn how to get access to the free-way of analytical tools that offer forward formulated physical functions to be fixed with non-linear fitting procedures. The approach I have taken is different from that of many other textbooks on the analysis of equilibrium dose-responses, which follow in the tradition of data-linearization developed more than 70 years ago. A book in point is Segel's ‘Enzyme kinetics’ (1975), reissued as a non-revised edition in 1993 and still considered a standard textbook on enzyme kinetics: it lacks almost completely in analysis of the so-called two-state models.״ http://www.merlot.org/merlot/viewMaterial.htm?id=433415 This free online textbook/course "aims to explain how scientists unravel the many different ways medicines work in the body and how this information guides the hunt for drugs of the future. Pharmacology is a broad discipline encompassing every aspect of the study of drugs, including their discovery and development and the testing of their action in the body. Much of the most promising pharmacological research going on at universities across the country is sponsored by the National Institute of General Medical Sciences (NIGMS), a component of the National Institutes of Health (NIH), U.S. Department of Health and Human Services.״ http://www.merlot.org/merlot/viewMaterial.htm?id=447254 This free, online textbook is designed primarily for those in the medical profession. Each chapter is written by a different doctor. Chapters include: * Phrase Book, * Acid-Base Physiology, * Airway Management, * Anesthetic Complications, * Cardiac Anesthesia, * Coexisting Diseases, * Critical Care, * Equipment, * Fluid Management, * Malignant Hyperthermia, * Obstetric Anesthesia, * Pain Management, * Regional Anesthesia, * Statistics, and * Trauma Anesthesia http://www.merlot.org/merlot/viewMaterial.htm?id=446269 According to the site, "Merck is committed to bringing out the best in medicine. As part of that effort, Merck has created The Merck Manuals, a series of healthcare books for medical professionals and consumers. As a service to the community, the content of The Manuals is now available in enhanced online versions as part of The Merck Manuals Online Medical Library.״This manual concerns Clinical Pharmacology and contains topics such as: Adverse Drug Reactions, Pharmacodynamics, and Pharmacokinetics. http://www.merlot.org/merlot/viewMaterial.htm?id=446476 This is a great resource for medical professionals in that it provides an alphabetical list of pharmaceuticals, one by generic name and one by trade name. According to the site, "Most prescription drugs have trade names (also called proprietary, brand, or specialty names) to distinguish them as being produced and marketed by a particular manufacturer. In the US, these names are usually registered as trademarks with the Patent Office, which confers certain legal rights with respect to their use. A trade name may be registered for a product containing a single active ingredient (with or without additives) or ≥ 2 active ingredients (combination drugs). A chemical substance marketed by several manufacturers may have several trade names. A drug may be marketed under different trade names in different countries. Trade names are found in many publications and are used extensively in clinical medicine. For convenience, the following table lists trade names for most drugs mentioned in The Manual, primarily those marketed in the US. The table is not all-inclusive and does not list every trade name for each drug. A few drugs in the table are investigational and may subsequently be approved by the FDA. Inclusion of a drug does not indicate approval of its use for any indication, nor does it imply efficacy or safety of its action. Inclusion of a trade name indicates neither endorsement nor preference by The Manual.״ http://www.merlot.org/merlot/viewMaterial.htm?id=447266 This is a free, online textbook that is an ongoing project, much like a wikibook. The goal of the textbook is "to organise all internet resources on anaesthesia into one concise, textbook style website." "The Virtual Anaesthesia Textbook is a collaborative project involving many individuals around the globe.״