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MERLOT II


    

Learning Exercise


Material: Actin-myosin crossbridge animation
Submitted by: Thomas Lonergan on Jan 11, 2002
Date Last Modified: Jan 11, 2002
Title: Interpretation of Three-Dimensional Model
Description: Students are asked to answer specific questions about the animated interaction between actin and myosin. Students should have prior knowledge of the general terminology of muscle contraction, such as "cross bridge and power stroke" prior to attempting this activity.
Type of Task: Individual, Supplemental activity, Unsupervised
Time Required 30 minutes
Topics: Animal physiology, cell biology, general biology
Course: Animal physiology, cell biology, general biology
Audience: College General Ed
Categories:
Prerequisites Skills: Knowledge of muscle contraction terminology, such as cross bridge, power stroke, ATP hydrolysis prior to attempting assignment.
Learning Objectives: Build on the traditional two-dimensional model of muscle contraction by accurately describing specific steps in an animation.
Learn to accurately describe steps in a complex process.
Demonstrate mastery beyond memorization.
Text of Learning Exercise: Answer the following questions.
1. In this animation, two events happen when calcium binds to troponin.
Describe these events.
2. What event happens immediately after magnesium binds to the myosin head
group?
3. What happens to the position of the myosin head group when ATP binds?
4. What happens to the position of the myosin head group when the ATP is
hydrolyzed and ADP is attached to the head group?
5. Why does the actin filament only move in one direction?
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