Note from the author. "This activity was written for a Microbiology course for health science students. However, it could be used in a variety of courses, and does not require much background knowledge of biology or microbiology. The main goal is to illustrate the relationship between the use of antibiotics and the proliferation of antibiotic-resistant strains of microbes, especially when antibiotics are improperly used. The activity can be used as supporting material for discussions on issues surrounding the use and misuse of antibiotics, and the increasing problem of drug-resistant microbes."