The Reactome represents a physiologist/cell biologist’s playground. Metabolic pathways offer a unique challenge to students and scientists alike. It can be difficult to visualize a pathway. The Reactome offers a peer-reviewed database for examining human metabolic processes. While the main portion of the site focuses on human processes, there is a way to compare human processes with other major organisms from other phyla, many of which are considered model organisms. The ability to analyze expression data and download Reactome data make this application a very useful and well developed website.
This site does not publish specific learning goals.
Target Student Population:
This website targets graduate students in cell biology, molecular biology, and bioinformatics programs.
Prerequisite Knowledge or Skills:
A firm understanding of gene expression, metabolism, and cell biology would be helpful in understanding these materials.
Type of Material:
This material is presented as an interactive metabolic pathway.
These materials are appropriate for graduate level studies and research.
The site requires the ability to play tutorial videos using Java. Users may also download the Cytoscape plugin, but this is only necessary for looking at protein interactions associated with cancer.
Evaluation and Observation
Peer-reviewed, expert annotated and collaborative database that is cross-referenced with major bioinformatics resources
Focused on human processes, but includes other important species
Multiple search and browsing tools
Provides analytical function on top of data storage and visualization
There were no concerns about quality of content at the time of this review
Potential Effectiveness as a Teaching Tool
Provides depth and complexity
Comparing species accesses higher levels of learning in Bloom’s taxonomy
Could help graduate students gain a better grasp of metabolic and cellular processes
This site requires a lot of preparation and training by instructors for students to use this tool effectively
Ease of Use for Both Students and Faculty
Browsing the pathways resembles using one of the major map applications from major search engines, which makes it familiar and easy to navigate
Tutorial video and other help resources
Multiple pathways to navigate to the various functions and tools
Contact information that includes Facebook and Twitter
The immense scope of the site could be overwhelming to some students without proper instructions and guidance