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Extinction of cue-evoked drug-seeking relies on degrading hierarchial instrumental expectancies

Extinction of cue-evoked drug-seeking relies on degrading hierarchial instrumental expectancies

There has long been need for a behavioural intervention that attenuates cue-evoked drug-seeking, but the optimal method remains obscure. To address this, we report three approaches to extinguish cueevoked drug-seeking measured in a Pavlovian to instrumental transfer design, in non-treatment seeking adult smokers and alcohol drinkers. The results showed that the ability of a drug stimulus to transfer control over a separately trained drug-seeking...

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