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The Cochrane Library: Chemotherapy alone versus endocrine therapy alone for metastatic breast cancer Intervention Review
This invervention reviews the effects of chemotherapy alone versus endocrine therapy alone for treating metastatic breast cancer. If the cancer has spread beyond the breast (metastatic disease), treatments include chemotherapy (anti-cancer drugs) and endocrine therapy (also known as hormonal treatment). The aim of this review was to see if starting treatment with chemotherapy or starting treatment with endocrine therapy provides more benefit in terms of survival, response to treatment, toxicity from treatment and quality of life. This review found that while initial treatment with chemotherapy rather than endocrine therapy might be associated with a higher response rate, the two initial treatments had a similar effect on overall survival.
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