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Construction of an Imitating Nano-motor Driven by Six ATP-binding RNAs of Bacterial Virus phi29

        

Construction of an Imitating Nano-motor Driven by Six ATP-binding RNAs of Bacterial Virus phi29

Logo for Construction of an Imitating Nano-motor Driven by Six ATP-binding RNAs of Bacterial Virus phi29
A switchable imitating DNA-packaging motor was constructed in the laboratory. The motor is driven by six synthetic ATP-binding pRNA (packaging RNA) molecules that bind to the connector and function in a manner similar to the driving of a bolt with a hex nut. Conformational change and sequential action of the RNA ensure continuous rotation of the motor, with ATP as energy.A 5-um DNA was packaged using this synthetic motor using one ATP to translocate two base pairs of DNA. The DNA-filled capsids... More
Material Type: Presentation
Date Added to MERLOT: February 16, 2006
Date Modified in MERLOT: February 16, 2006
Author:
Submitter: nanoHUB

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Primary Audience: College General Ed
Mobile Compatibility: Not specified at this time
Language: English
Cost Involved: no
Source Code Available: no
Accessiblity Information Available: no
Creative Commons: unsure

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