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Lecture 2: Replication Timing
This video was recorded at Lecture Series by Howard Cedar: Epigenetics and Methylation. Professor Cedar explains how the DNA methylation pattern is established in development. Starting with the embryo, he shows how initially DNA lacks methylation, and how during development, the methylation pattern is established. This pattern is then preserved throughout organismal growth, based on a novel regulatory mechanism that preserves the original template. Specifically, Professor Cedar explains what elements within the DNA sequence are responsible for establishing these methylation sites.
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