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Mathematical Modeling of Cell Signalling Pathways

Mathematical Modeling of Cell Signalling Pathways

This video was recorded at Workshop on Practical Inference Methods for Mechanistic Modelling of Biological Systems (PIMMS), Glasgow 2007. In recent years, the analysis of cell signalling systems through data-based models in ordinary differential equations (ODE) or other paradigms (e.g. stochastic models) has emerged as an invaluable tool to understand the underlying complexity of the protein interactions happening in cellular signal transduction. Compared with other biochemical systems, the modelling of cell signalling systems faces additional difficulties related to the challenges quantifying protein-protein processes but also to the lack of complete information about the topology of the considered network interactions. Since in most of the metabolic systems the complete network of... Show More

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