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This video was recorded at Workshop on Probabilistic Modelling of Networks and Pathways, Sheffield 2007. Experimental advances in molecular biology are providing deeper understanding in the workings of living cells. High throughput functional genomic techniques are providing researchers with a reliable map of the complex networks underpinning the functioning of cells. Cellular processes often involve complex networking of several genes and transcription factors, and their temporal structure can often be accurately described in terms of pathways. A key problem in obtaining a computational understanding of these systems is the incomplete and noisy nature of most data: while certain relevant quantities, such as mRNA concentrations, can be measured accurately in a high throughput fashion,... Show More


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