Learning Exercise

Interpretation of Three-Dimensional Model

Students are asked to answer specific questions about the animated interaction between actin and myosin. Students should have prior knowledge of the general terminology of muscle contraction, such as "cross bridge and power stroke" prior to attempting this activity.
Course: Animal physiology, cell biology, general biology
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The actin-myosin crossbridge system is complex, and we are really only speculating on the details in many ways. However,... see more

Exercise

Answer the following questions.
1. In this animation, two events happen when calcium binds to troponin.
Describe these events.
2. What event happens immediately after magnesium binds to the myosin head
group?
3. What happens to the position of the myosin head group when ATP binds?
4. What happens to the position of the myosin head group when the ATP is
hydrolyzed and ADP is attached to the head group?
5. Why does the actin filament only move in one direction?

Audience

Requirements

Knowledge of muscle contraction terminology, such as cross bridge, power stroke, ATP hydrolysis prior to attempting assignment.

Topics

Animal physiology, cell biology, general biology

Learning Objectives

Build on the traditional two-dimensional model of muscle contraction by accurately describing specific steps in an animation.
Learn to accurately describe steps in a complex process.
Demonstrate mastery beyond memorization.