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Peer Review

Activation of Tyrosine Kinase Receptor

by McGill Molson Medical Informatics Project


Overall Numeric Rating:

3 stars
Content Quality: 2.75 stars
Effectiveness: 3 stars
Ease of Use: 3.5 stars
Reviewed: Dec 17, 2012 by Biology Editorial Board
Overview: Flash driven model of the activation of Tyrosine Kinase Receptor and its outputs after activation
Type of Material: Flash animation
Recommended Uses: In class demonstration of tyrosine kinase receptor activation.
Technical Requirements: Flash plug-in
Identify Major Learning Goals: See what happens when tyrosine kinase activates and what downstream activities occur Supplementary information to see how the receptor interacts with the environment
Target Student Population: Undergraduate
Prerequisite Knowledge or Skills: Cell biology or biochemistry

Evaluation and Observation

Content Quality

Rating: 2.75 stars
  • A reasonably accurate animation of how a tyrosine kinase receptor would dimerize upon binding to a ligand and phosphorylate cytoplasmic residues.
  • Concerns:
  • The animation does not contain any text to explain what is happening, how the phosphates appear, the role of ATP, etc.
  • As it stands the instructor would have to explain all of the details.
  • Wanted some background information Wanted explanation of what is Tyrosine Kinase Receptor More downstream activities

  • Potential Effectiveness as a Teaching Tool

    Rating: 3 stars
  • This would be effective as in-class demonstration.
  • Concerns:
  • This would not be very useful as a stand alone activity for students.
  • As there is not any text to explain the animation it would be difficult to make assignments based on this animation.
  • Move too fast wanted explenation of what ws occuring

  • Ease of Use for Both Students and Faculty

    Rating: 3.5 stars
  • Very simple animation with only a play button.
  • Concerns:
  • none

  • Other Issues and Comments:
  • Great to add to a power point and visuals are excellent