Peer Review

Nuclear Contents: DNA and Proteins

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Reviewed:: Apr 18, 2006 by Biology

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Ratings

Overall Rating:

Content Quality:

Effectiveness:

Ease of Use:

Overview:: This module on Nuclear Contents: DNA and Protein, is from the Supersite "DNA From the Beginning." The focus of this learning object is on DNA and protein as key molecules of the cell nucleus. The works of Friedrich Miescher and Theodor Levene are described to show how the composition and nature of nuclear molecules were discovered. This unit is organized as a set of about a dozen concepts that delineate how scientists came to understand the structure of DNA and proteins. The animated tutorial shows the basic experimental design(s) that lead to an understanding of how DNA and proteins were putp together. Users may access the "Problem" menu, which presents several multiple choice questions requiring interpretation of the experimental results presented in the tutorial. The questions are instantly graded, providing immediate feedback. Additional menus are: the "Picture Gallery," with images of historical photographs of researchers, lab, and laboratory equipment used in the experiments described; the "Audio/Video" menu, that presents QuickTime interviews with researchers who discuss the concept in more detail; and a "Biography" menu, providing further information about the key scientists. A "Links" menu provides further bibliographic information, as well as links to additional relevant sites.
Type of Material:: Tutorial and Animation / Interactive Lesson
Recommended Uses:: This material can be used in lecture or for independent study to learn about molecular genetics.
Technical Requirements:: Flash Player and QuickTime are needed to see animations and view video clips.
Identify Major Learning Goals:: Understanding the structure of the four nucleotides and how they are linked into a polymer and the early theories about what the genetic material might be.
Target Student Population:: Advanced high school as well as undergraduate and graduate students
Prerequisite Knowledge or Skills:: No prerequisite knowledge is required, but some background in chemistry, genetics, and molecular biology may help users better understand the information.

Content Quality

Rating:

Strengths:

Clearly laid out, well organized, and very well presented
Very complete and accurate information with appropriate vocabulary
Content follows a logical progression, both conceptually and chronologically
Animations accurately represent experimental designs presented
Exceptional combination of animation and video interviews
The breadth of coverage is impressive and complete

Concerns:

The site needs more video interviews from other scientists. A few female and minority scientists would be a plus for this part of the site. These interviews are valuable tools for learning and understanding the methods of science.

Potential Effectiveness as a Teaching Tool

Rating:

Strengths:

Excellent source of tutorial information
Tutorials promote understanding of basic concepts and contain more than one approach to understanding the concept
Tutorial animations and problems lend themselves to the creation of additional questions such as "where do we go from here?"
Interactive quizzes provide immediate reasons for correct and incorrect answers
Video interviews with famous scientists provide motivation for student learning
The animations represent an excellent collection of scientific reasoning and logic, and focus on "how we know" not just "what we know." The animations frequently begin with a famous scientist posing a problem to be solved. This approach may make more of a connection between the results of a classical experiment and the mind behind the reasoning. The constant flow of scientific reasoning from unit to unit provides a clear and impressive thread of logic showing how scientists realized that DNA is the genetic material.

Concerns:

The tutorials could be improved by adding sound and expanding upon the interactivity of some of the Flash Player animations

Ease of Use for Both Students and Faculty

Rating:

Strengths:

Clear and accurate instructions
Well designed, easy to navigate, intuitive and fast
Widespread and effective use of animation
Definitions linked directly to the term
Excellent use of Flash Player and QuickTime video clips

Concerns:

None

Other Issues and Comments:: The animations represent an excellent collection of scientific reasoning and logic, and focus on "how we know" not just "what we know." The animations frequently begin with a famous scientist posing a problem to be solved. This approach may make more of a connection between the results of a classical experiment and the mind behind the reasoning. The constant flow of scientific reasoning from unit to unit provides a clear and impressive thread of logic showing how scientists realized that DNA is the genetic material. It might help to add more video interviews from other scientists, especially where there is only one person featured in the video clips. Perhaps modern scientists could substitute for those who cannot be interviewed. A few female and minority scientists would be a plus for this part of the site. These interviews are valuable tools for learning and understanding the methods of science. The authors might consider adding sound and expand upon the interactivity of some of the Flash Player animations.
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