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An Oral Contraceptive Drug Interaction Study

An Oral Contraceptive Drug Interaction Study

This article, created by Thomas E. Bradstreet and Deborah L. Panebianco of Merck Research Laboratories, describes data from a drug interaction study of a new drug and a standard oral contraceptive therapy. Both normal theory and distribution-free statistical analyzes are provided along with a notable amount of graphical insight into the dataset. The article itself contains sections such as: an introduction, bioavailability, bioequivalence, interaction studies, motivation for the study, an initial exploration of the data, the model with ANOVA, software employed and references. This is an excellent look at the procedures behind medical testing.

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