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Drug Design: Protein Kinases

Drug Design: Protein Kinases

In this activity, by the Concord Consortium's Molecular Literacy project, students "review protein structure and hydrophilic/phobic interactions, and then study kinases, small proteins that regulate numerous cell processes." The activity itself is a java-based interactive resource built upon the free, open source Molecular Workbench software. In the activity, students are allowed to explore at their own pace in a digital environment of demonstrations and simulations which allow them to print reports of data captured. There are six pages: an Introduction, Inter/intramolecular attractions: Types of Bonds, Inter/intramolecular attractions: Hydrophobic Interactions, Inter/intramolecular attractions: Hydrophilic Interactions, Protein Kinase Example: Tertiary Structure, and Protein Kinase Example: Ligand Bonding and Drug Design.

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