Zirconium oxide and silicon dioxide powders are selected and subjected to a non-contact Biofield energy known to be transmitted by Mahendra Kumar Trivedi. Particle sizes d50 and d99 showed up to 71.5 percent decrease indicating that the energy had caused deformation and fracture as if the powders have been subjected to high energy milling. This is also supported by increase in specific surface area up to 19.48 percent. In the present investigation Zirconium oxide and silicon dioxide powders are exposed to Bio-field. Both the exposed and unexposed powders are later characterized by various techniques. The treated powders when characterized by X-ray diffraction are found to exhibit significant increase and decrease in the lattice parameters of the unit cell, crystallite size and density. The lattice parameters are then used to compute the molecular weight and total number of protons and neutrons in the molecule, which showed an increase up to 0.24 and decrease up to 0.31 percent. It is speculated that the Biofield energy transmitted by Mr. Trivedi is acting on the nucleus in the atoms through some reversible weak interaction of larger cross section causing changes in the proton to neutron ratios and thus energy to mass and mass to energy. Thus the effect is felt by all the atoms, and hence the unit cell, single crystal grain and grain boundaries. The stresses generated in turn may have caused deformation and fracture of the weak interfaces in the polycrystalline powders such as the crystallite and grain boundaries.