Thin Layer Chromatography (TLC) Simulator
This interactive animation explores the effects of the polarity of the organic compounds and the polarity of the solvent mixture on a silica gel TLC analysis. Two TLC chambers are provided so the user can select a different solvent combination for each, and run a side-by-side comparison. Available eluents include 100% hexane, 75:25 hexane:ethyl acetate, 50:50, 25:75 hexane:ethyl acetate, and 100% ethyl acetate. To help achieve the student learning outcomes, a summary is provided at the end of each simulation and an accompanying worksheet has been developed to guide the activity. An accessible version is available with the click of a button.