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National Cancer Institute: Genetics of Skin Cancer

National Cancer Institute: Genetics of Skin Cancer

NCI's informational section about the genetics and types of skin cancer. There are more than 100 types of tumors that are clinically apparent on the skin; many of these are known to have familial components, either in isolation or as part of a syndrome with other features. This is, in part, because the skin itself is a complex organ made up of multiple cell types. Furthermore, many of these cell types can undergo malignant transformation at various points in their differentiation, leading to tumors with distinct histology and dramatically different biological behaviors, such as squamous cell cancer (SCC) and basal cell cancers (BCC). In addition to malignant tumors, there are also many types of benign tumors.
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