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ACTH action in the adrenal Cortex: From molecular biology to pathophysiology

ACTH action in the adrenal Cortex: From molecular biology to pathophysiology

By stimulating adrenal corticosteroid synthesis, the adrenocorticotropic hormone (ACTH) plays a pivotal role in homeostasis and stress response. In this Research Topic, we will discuss the various mechanisms involved in ACTH action, from ACTH binding to its receptor to steroid secretion, as well as the pathological consequences of the disruption of specific components of the pathways. A particular attention will be given to how various kinases,...

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