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related adverse events (IRAEs) in peripheral veins. A growing number of studies have reported relatively safe administration of 3% NaCl through a peripheral vein. The incidences of IRAEs were evaluated in 9 studies that included 837 patients who received 3% NaCl through a peripheral vein. Infusion reactions were either uncommon or no more frequent than with routine solutions. The authors provide guidelines for the administration of and monitoring for complications associated with 3% NaCl through a peripheral vein, discuss the management of symptomatic hyponatremia, and provide illustrative cases....

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