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TransportDB

TransportDB

TransportDB is a relational database describing the predicted cytoplasmic membrane transport protein complement for organisms whose complete genome sequence are available. One can also compare the transporter system from different organisms or perform a blast search of a protein sequence against the transporter database.

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liwei zhou
liwei zhou (Staff)
21 years ago
This work, by Dr. Qinghu Ren from The Institute for Genomic Research, includes
the identification and characterization all existing membrane transporters in
those microorganisms and eukaryotic species for which extensive genome sequence
data are available. For each organism, the complete set of membrane transport
systems was identified and classified into different types and families
according to putative membrane topology, protein family, bioenergetics, and
substrate specificities. This is the only database devoted to the identification
and classification of all transporter homologues in complete genomes, as well
as providing comparative and phylogenetic tools for analyzing data. I definitely
recommend to the research and academic community as well as college and
graduate student as an excellent learning and reference material.

Technical Remarks:

Dr. Qinghu Ren?s marvelous work requires strong background in both molecular
biology and computer science. TransportDB is a relational database which will
be regularly updated with data obtained from newly sequenced genomes.
User-friendly web pages provide interfaces to easily access, query, and download
the data. Additional features, such as a BLAST search tool against known
transporter protein sequences, comparison of transport systems from different
organisms, and phylogenetic trees of individual transporter families are also
provided.
Used in course? Yes
Dongying Wu
Dongying Wu (Staff)
21 years ago
general remarks: This work, by Dr. Qinghu Ren from The Institute for
Genomic Research, includes the identification and characterization all existing
membrane transporters in those microorganisms and eukaryotic species for which
extensive genome sequence data are available. For each organism, the complete
set of membrane transport systems was identified and classified into different
types and families according to putative membrane topology, protein family,
bioenergetics, and substrate specificities. This is the only database devoted to
the identification and classification of all transporter homologues in complete
genomes, as well as providing comparative and phylogenetic tools for analyzing
data. I definitely recommend to the research and academic community as well as
college and graduate student as an excellent learning and reference material.

Technical Remarks:

technical remarks: Dr. Qinghu Ren?s marvelous work requires strong
background in both molecular biology and computer science. TransportDB is a
relational database which will be regularly updated with data obtained from
newly sequenced genomes. User-friendly web pages provide interfaces to easily
access, query, and download the data. Additional features, such as a BLAST
search tool against known transporter protein sequences, comparison of transport
systems from different organisms, and phylogenetic trees of individual
transporter families are also provided.