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Abstract. This article presents a pedagogical framework using questionbased learning (QBL) in nanoscience, nanotechnology, and their applications in medicine and engineering. This paper aims to create a multidisciplinary learning resource centered on question-based learning (QBL) that serves as a comprehensive and valuable reference for educators and students. QBL involves actively posing questions, gathering and analyzing information, building and applying knowledge, developing deep conceptual understanding, exploring creative possibilities, making informed decisions, and justifying conclusions through critical reasoning. To achieve these objectives, a qualitative literature survey was conducted utilizing platforms such as Google Scholar, Scopus, PubMed, and public repositories. This module presents examples of 66 structured questions covering interdisciplinary aspects of nanoscience/technology. This question-and-answer activity has attracted significant interest and excitement, as an active exercise in education, an increasingly important part of the student’s transformational process in the higher education system.

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