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"Bioinformatics and Systems Biology:  At the Crossroads of Biology, Engineering and Computation" icon

Bioinformatics and Systems Biology: At the Crossroads of Biology, Engineering and Computation

Traditional biological research has relied on a "deconstructive" mode where piece-wise analysis of the components of complex systems was carried out in detail. The genome projects have spurred the discovery of new genes/molecules to add to the existing inventory of "parts" that make up living entities. With the availability of this information and the development of increasingly powerful tools for global analysis of gene and protein expression (chips/arrays), a "constructionist" bias has begun to appear in biology. There is a growing desire to put integrate the piecewise knowledge and achieve a deeper understanding of how living systems work as total entities. "This attempt to develop a true understanding of how living beings are "engineered" so that the emergent properties of the assembled... Show More
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