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What Harm Does Pathological Synchronization in Parkinson's Disease Do?

What Harm Does Pathological Synchronization in Parkinson's Disease Do?

This video was recorded at The Basal Ganglia in Health and Disease. Like tuning in a station on the FM band of a radio, neuroscientists can detect the particular frequencies of our brains in action. And just as on the radio, a little noise and static is to be expected. In Parkinson's Disease (PD), as Peter Brown and colleagues are finding, too much of a certain type of frequency is a bad thing. Neurons in the basal ganglia produce a kind of overly synchronized beta frequency (in the 20 Hz range) that seems deeply implicated in some of the telltale symptoms of Parkinson's. Brown's talk outlines efforts to record this "oscillatory synchrony" in PD, to figure out the physiological mechanisms behind it, and to connect beta synchrony directly to such key symptoms in PD patients as rigidity and... Show More

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