Learning Exercise

Superimpose aligned protein sequences onto a structure

Students use Biology Workbench and Protein Explorer to align either orthologous or paralogous sequences and then superimpose these onto a 3D structure of one member of the protein family.

Course: Bioinformatics, Molecular Biology, Biochemistry

Material:: Protein Explorer
Date last modified:: June 24, 2003
Created by:: Scott Cooper
License:

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Protein Explorer

Protein Explorer became non-operational about 2008. It is replaced with FirstGlance.Jmol.Org (for guided exploration of... see more

Material Type:: Simulation
Author:: Eric Martz, University of Massachusetts
User Rating:: 5 stars

Exercise

See link for text.

Disciplines

Audience

High School

Technical Notes

Requires Chimes plug-in to run protein explorer

Requirements

Understanding of biochemistry and molecular biology

Topics

Bioinformatics
Protein Structure
Evolution

Type of Task

Learning Objectives

For students to explore the sequence similarities in orthologs and paralogs