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Although the importance of an accurate diagnosis has been emphasized repeatedly above, finding an effective treatment strategy is also vitally important. The 1999 Multimodal Treatment Study of ADHD (MTA Study) is the largest study (involving approximately 570 children over 6 different sites in the United States and Canada) to date comparing the effectiveness of different treatments for ADHD. The results from the MTA study showed that medication was the single most effective treatment. However, the most effective treatment strategy overall was a combination of medication and psychosocial treatments (social skills training or anger management training). The MTA results are groundbreaking in suggesting that medication is not the only option for people with ADHD and that combination therapy will likely provide the most positive impact.

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