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The Cochrane Library: Radiotherapy versus open surgery versus endolaryngeal surgery (with or without laser) for early laryngeal squamous cell cancer Intervention Review
Cancer of the larynx (voice box) usually begins in the glottis (vocal cords) as a squamous cell cancer (cancer in the membranes). Most people survive these cancers when they get treatment early (before the cancer spreads further into the larynx and surrounding area). Options include radiotherapy, open surgery (through the neck) or, more commonly now, endolaryngeal excision (surgery reaching the throat via the mouth, sometimes with a laser). The review of trials found there is not enough evidence to show which form of treatment might be better for people with early stage laryngeal squamous cell carcinoma. Such evidence may come from new trials comparing radiotherapy and endolaryngeal excision, which have started.
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