Magnesium plays important role in the functioning of cells, nerves, muscles, and bones of human body. It is incorporated in the form of magnesium gluconate in various pharmaceutical and nutraceutical supplements due to its wide applications. This study was done with the objective to analyse the effect of The Trivedi Effect®- Energy of Consciousness Healing Treatment on the physical, thermal, and spectral properties of magnesium gluconate. In this regard, the sample of magnesium gluconate was divided in two parts, in which first part was kept untreated and termed as control sample. Besides, the second part was remotely treated by the renowned Biofield Energy Healer, Mr. Mahendra Kumar Trivedi with The Trivedi Effect®- Biofield Energy Healing Treatment and termed as Biofield Energy Treated sample. Consequently, both the samples were analyzed using PXRD, PSA, DSC, TGA/DTG, UV-Vis, and FT-IR analytical techniques. The PXRD analysis revealed that the crystallite sizes and relative peak intensities of the treated sample showed variations in the range of-25.01% to 185.79% and 6.99% to 32.99%, respectively along with 13.03% increase in average crystallite size as compared to the control sample. The particle sizes d10, d50, d90, and D(4,3) values of the treated sample were significantly decreased by 3.70%, 21.88%, 22.03%, and 21.16%, respectively, along with 10.75% increase in the surface area as compared to the control sample. The DSC studies showed minor decrease in melting point (0.10%) with 3.74% increase in the latent heat of fusion of the treated sample, compared to the control sample. Besides, The TGA/DTG analysis represented alterations in the weight loss pattern and maximum thermal degradation temperature (Tmax) of the treated sample. The analysis revealed three steps thermal degradation, in which the variation was observed from -6.79% to 10.14% in terms of weight loss along with 0.24% increase in the total weight loss of the treated sample, compared to the control sample. The Tmax of the first two peaks were found to be increased by 6.90% and 1.28%, while 3rd and 4th peaks were slightly decreased by 0.57% and 0.24% in the treated sample, compared to the control sample. The Energy of Consciousness Healing Treatment might produce a new polymorphic form of magnesium gluconate, which may have a better solubility, absorption and bioavailability profile along with altered thermal stability compared to the untreated sample. Thus, the Biofield Energy Treated magnesium gluconate would be helpful in designing the better nutraceutical/pharmaceutical formulations with better therapeutic responses against the magnesium deficiency.
