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Leading Innovation

Leading Innovation

This video was recorded at MIT Leadership Center. Since innovation is "not necessarily always predictable," Daniel Vasella declines to discuss it in a systematic way, and instead, focuses on a case study of one of his company's flagship pharmaceuticals, Gleevec. The discovery, development and marketing of this drug, which fights the rare chronic myeloid leukemia (CML), may point to some of the things Novartis does right, suggests Vasella. Many significant drugs result from years of basic research that takes place outside of industry. Pathbreaking work that occurred decades ago uncovered chromosome damage in patients with CML, and revealed an abnormal protein secreted due to this mutation. In the early 1990s, Novartis began the creative work of trying to block the signal of this... Show More

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