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Statistical Inference of Protein Structure and Function

Statistical Inference of Protein Structure and Function

This video was recorded at 24th Annual Conference on Neural Information Processing Systems (NIPS), Vancouver 2010. The study of the structure and function of proteins serves up many problems that offer challenges and opportunities for computational and statistical research. I will overview my experiences in several such problem domains, ranging from domains where off-the-shelf ideas can be fruitfully applied to domains that require new thinking. These are: the identification of active sites in enzymes; the modeling of protein backbone configurations; the prediction of molecular function based on phylogeny; alignment and phylogenetic inference.


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