Abstract This work introduces a graphic causality system for gastrointestinal (GI) physiology, designed to address the limitations of traditional teaching tools by standardizing the visualization of regulatory mechanisms. Current methods often rely on fragmented diagrams and linear cascades, which obscure the dynamic, circular nature of physiological feedback. In contrast, this framework employs bidirectional radial axes and directional vectors to model interactions between parameters (e.g., hormones, pH, motility), enabling intuitive pattern recognition of homeostasis and its disruptions. Key features include: - Modular design, allowing scalable complexity—from basic two-axis loops (e.g., gastrin-HCl feedback) to multi-loop integration (e.g., gastric acid- gastric emptying regulations). - Clinical anchors that directly link vector configurations to high-yield pathologies (e.g., Zollinger-Ellison syndrome, H. pylori ulcers). - Consistent visual grammar, reducing cognitive load while reinforcing cross-system principles. Designed as a complement to textbooks, this system empowers learners to transition from memorization to mechanistic reasoning, with applications ranging from preclinical instruction to clinical problem-solving.
Methodology Notice: All diagrams in this manuscript were created using the Dr Mihăilă Graphic System®, a standardized visual method for transforming causal relationships into intuitive geometric models (multi‑axis structures and circular‑arc feedback systems). This graphical methodology has been fully detailed in our foundational work and is applied here to the specific domain addressed in this manuscript.
Trademark Notice: Dr Mihăilă Graphic System® is an officially registered trademark under the European Union Intellectual Property Office (EUIPO).
Keywords: GI physiology, feedback loops, causal modeling, gastric acid regulation, gastric emptying model, visual pedagogy.